Sarcomatoid carcinoma of pancreas with liver metastases – A case report with review of literature

Sarcomatoid carcinoma is a rare, high-grade epithelial malignancy composed exclusively or predominantly of spindle cells often having features suggestive of epithelial derivation without features indica tive of a specific line of mesenchymal differentiation. Sarcomatous carcinomas occur in diverse locations throughout the body, including the upper respiratory tract, upper and lower digestive tracts, genitourinary tract, breast and thyroid glands, among others. Sarcomatoid carcinoma rarely presents in the pancreas. The current study presents the case of a 41-year-old male with a tumor mass in the uncinate of the pancreas and liver metastases. Histopathology and immunohistochemistry of the liver metastases were confirmatory of metastatic sarcomatoid carcinoma. To the best of our knowledge, only nine cases of pancreatic sarcomatoid carcinoma have been reported in literature. Correspondence to: Rakul Nambiar K, Division of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India, E-mail: [email protected]